Endoplasmic reticulum resident proteins

class of enzymes

protein-coding gene in the species Homo sapiens

Calsequestrin is a calcium-binding protein that acts as a calcium buffer within the sarcoplasmic reticulum. The protein helps hold calcium in the cisterna of the sarcoplasmic reticulum after a muscle contraction, even though the concentration of calcium in the sarcoplasmic reticulum is much higher than in the cytosol. It also helps the sarcoplasmic reticulum store an extraordinarily high amount of calcium ions. Each molecule of calsequestrin can bind 18 to 50 Ca2+ ions. Sequence analysis has suggested that calcium is not bound in distinct pockets via EF-hand motifs, but rather via presentation

Thioredoxin-related transmembrane protein 1 is a protein that in humans is encoded by the TMX1 gene.

ER lumen protein retaining receptor 2 is a protein that in humans is encoded by the KDELR2 gene.

ER lumen protein retaining receptor 3 is a protein that in humans is encoded by the KDELR3 gene.

DnaJ homolog subfamily C member 10 is a protein that in humans is encoded by the DNAJC10 gene.

Thioredoxin domain-containing protein 5 is a protein that in humans is encoded by the TXNDC5 gene.

Thioredoxin domain-containing protein 12 is a protein that in humans is encoded by the TXNDC12 gene.

Protein disulfide isomerase family A member 2 is a protein that in humans is encoded by the PDIA2 gene.

Anterior gradient protein 3 homolog is a protein that in humans is encoded by the AGR3 gene.