POU-domain proteins

Oct-4 (octamer-binding transcription factor 4), also known as POU5F1 (POU domain, class 5, transcription factor 1), is a protein that in humans is encoded by the POU5F1 gene. Oct-4 is a homeodomain transcription factor of the POU family. It is critically involved in the self-renewal of undifferentiated embryonic stem cells. As such, it is frequently used as a marker for undifferentiated cells. Oct-4 expression must be closely regulated; too much or too little will cause differentiation of the cells.

POU domain, class 4, transcription factor 3 is a protein that in humans is encoded by the POU4F3 gene. It's a member of BRN-3 group, also known as POU family class 4.

POU domain, class 2, transcription factor 3 is a protein that in humans is encoded by the POU2F3 gene.

POU domain, class 2, transcription factor 1 is a protein that in humans is encoded by the POU2F1 gene.

POU domain, class 3, transcription factor 2 is a protein that in humans is encoded by the POU3F2 gene.

POU domain, class 4, transcription factor 2 is a protein that in humans is encoded by the POU4F2 gene.

POU domain, class 3, transcription factor 1 (also known as Oct-6) is a protein that in humans is encoded by the POU3F1 gene.