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GeneQ18030673· pop 6· linked from 893 articles

POU4F3

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Also known as BRN3C, DFNA15, POU class 4 homeobox 3, DFNA42, DFNA52

POU domain, class 4, transcription factor 3 is a protein that in humans is encoded by the POU4F3 gene. It's a member of BRN-3 group, also known as POU family class 4.

Gene data

POU4F3
Name
POU class 4 homeobox 3
Type
protein-coding
Position
146,338,648–146,341,728 (+)
Aliases
BRN3C, DFNA15, DFNA42, DFNA52
Ensembl
ENSG00000091010
RefSeq RNA
NM_002700.3
RefSeq protein
NP_002691.1

This gene encodes a member of the POU-domain family of transcription factors. POU-domain proteins have been observed to play important roles in control of cell identity in several systems. This protein is found in the retina and may play a role in determining or maintaining the identities of a small subset of visual system neurons. Defects in this gene are the cause of non-syndromic sensorineural deafness autosomal dominant type 15. [provided by RefSeq, Mar 2009].

Gene Ontology

via MyGene.info

Gene · Ensembl

POU class 4 homeobox 3

Symbol
POU4F3
Biotype
Protein coding
Organism
Homo sapiens
Location
5:146,338,648-146,341,728
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Show 8 more facts
exact match
identifiers.org/ncbigene/5459
found in taxon
Homo sapiens
HomoloGene ID
2023
genomic end
146341728
genomic start
146338839
chromosome
human chromosome 5
cytogenetic location
5q32
genetic association
nonsyndromic deafness
Sources (5)

via Wikidata · CC0

~1 min read

Encyclopedic overview

4 sections
Contents
  • Nomenclature
  • References
  • Further reading
  • External links

POU domain, class 4, transcription factor 3 is a protein that in humans is encoded by the POU4F3 gene. It's a member of BRN-3 group, also known as POU family class 4.

==Nomenclature== DFNA15 refers to a type of nonsyndromic deafness, with autosomal dominant inheritance.

Excerpted from Wikipedia’s “POU4F3” article, available under the CC BY-SA 4.0 licence.

Available in 6 languages

via Wikidata sitelinks · CC0