2,2,2-trifluoroethanol

2,2,2-Trifluoroethanol is the synthetic organic compound with the formula CF3CH2OH. Also known as TFEA or trifluoroethyl alcohol, this colourless, water-miscible liquid has a smell reminiscent of ethanol. Due to the electronegativity of the trifluoromethyl group, this alcohol exhibits a stronger acidic character compared to ethanol.

Research

2,733 papers

2,2,2-Trifluoroethanol-mediated hydroarylation of fluorinated alkynes with indoles: Application to diindolylmethanes.Archiv der Pharmazie · 2022
2,2,2-Trifluoroethanol toxicity in aged rats.Toxicologic pathology · 1988
Interactions of 2,2,2-trifluoroethanol with melittin.Magnetic resonance in chemistry : MRC · 2009
Multiple aspects of the toxicity of fluroxene and its metabolite 2,2,2-trifluoroethanol.Critical reviews in toxicology · 1988
2,2,2-Trifluoroethanol toxicity in hamsters (Mesocricetus auratus).Toxicologic pathology · 1987

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Article

7 sections

Contents

Synthesis
Properties
Reactions
Safety
See also
References
External links

==Synthesis== Trifluoroethanol is produced industrially by hydrogenation or the hydride reduction of derivatives of trifluoroacetic acid, such as the esters or acyl chloride.