Structure via PubChem · Public domain (PubChem)
fluroxene
Sign in to saveAlso known as 2,2,2-Trifluoroethoxyethene, 2,2,2-Trifluoroethyl vinyl ether, Fluoromar
Fluroxene (INN, USAN; brand name Fluoromar), or 2,2,2-trifluoroethyl vinyl ether, is a volatile, inhalational anesthetic. It was synthesized in 1951, and was introduced for clinical use in 1954, but was voluntarily withdrawn from the market in 1974 due to its potential flammability and accumulating evidence that it could cause organ toxicity. In any case, prior to being discontinued, it had largely been superseded by halothane. Fluroxene is metabolized to 2,2,2-trifluoroethanol, a compound responsible for some of the toxicity seen with fluroxene use.
Chemical data
- Formula
- C4H5F3O
- Molecular weight
- 126.08 g/mol
- IUPAC name
- 2-ethenoxy-1,1,1-trifluoroethane
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 126.029
Show 10 more facts
- chemical formula
- C₄H₅F₃O
- canonical SMILES
- C=COCC(F)(F)F
- NIOSH Pocket Guide ID
- 0291
- density
- 1.14
- boiling point
- 109
- vapor pressure
- 286
- ceiling exposure limit
- 10.3
- global warming potential
- 1
- has characteristic
- flammable liquid
- Commons category
- Fluroxene
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Fluroxene (INN, USAN; brand name Fluoromar), or 2,2,2-trifluoroethyl vinyl ether, is a volatile, inhalational anesthetic. It was synthesized in 1951, and was introduced for clinical use in 1954, but was voluntarily withdrawn from the market in 1974 due to its potential flammability and accumulating evidence that it could cause organ toxicity. In any case, prior to being discontinued, it had largely been superseded by halothane. Fluroxene is metabolized to 2,2,2-trifluoroethanol, a compound responsible for some of the toxicity seen with fluroxene use.
== See also == Divinyl ether Thiomethoxyflurane
Excerpted from Wikipedia’s “fluroxene” article, available under the CC BY-SA 4.0 licence.