Structure via PubChem · Public domain (PubChem)
3α-androstanediol
Sign in to saveAlso known as 17beta-dihydroandrosterone, 3alpha-androstanediol, 3alpha,17beta-dihydroxy-5alpha-androstane, 3α,17β-dihydroxy-5α-androstane, Dihydroandrosterone, hombreol, (3alpha,5alpha,17beta)-androstane-3,17-diol, 5alpha-androstane-3alpha,17beta-diol
3α-Androstanediol also known as 5α-androstane-3α,17β-diol and sometimes shortened in the literature to 3α-diol, is an endogenous steroid hormone and neurosteroid and a metabolite of androgens like dihydrotestosterone (DHT).
Chemical data
- Formula
- C19H32O2
- Molecular weight
- 292.5 g/mol
- IUPAC name
- (3R,5S,8R,9S,10S,13S,14S,17S)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol
- SMILES
- C[C@]12CC[C@H](C[C@@H]1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC[C@@H]4O)C)O
- InChIKey
- CBMYJHIOYJEBSB-KHOSGYARSA-N
- XLogP
- 4.2
- Polar surface area
- 40.5 Ų
- H-bond donors
- 2
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Mass
- 292.24023
Show 4 more facts
- chemical formula
- C₁₉H₃₂O₂
- canonical SMILES
- CC12CCC(CC1CCC3C2CCC4(C3CCC4O)C)O
- isomeric SMILES
- C[C@]12CC[C@H](C[C@@H]1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC[C@@H]4O)C)O
- found in taxon
- Daphnia magna
via Wikidata · CC0
~2 min read
Encyclopedic overview
4 sectionsContents
- Biological activity
- Biochemistry
- Chemistry
- References
3α-Androstanediol also known as 5α-androstane-3α,17β-diol and sometimes shortened in the literature to 3α-diol, is an endogenous steroid hormone and neurosteroid and a metabolite of androgens like dihydrotestosterone (DHT).
==Biological activity== 3α-Androstanediol is an inhibitory androstane neurosteroid and weak androgen and estrogen.
Excerpted from Wikipedia’s “3α-androstanediol” article, available under the CC BY-SA 4.0 licence.