androstenol
Sign in to saveAlso known as androst-16-en-3-ol, 3α-androstenol, 5α-androsten-3α-ol, 16,17-Androstene-3-Ol
Androstenol, also known as 5α-androst-16-en-3α-ol (shortened to 3α,5α-androstenol or 3α-androstenol), is a 16-androstene class steroidal pheromone and neurosteroid in humans and other mammals, notably pigs. It possesses a characteristic musk-like odor.
Research
90,410 papers- Androstenol--a steroid derived odor activates the hypothalamus in women.PloS one · 2010
- The pheromone androstenol (5 alpha-androst-16-en-3 alpha-ol) is a neurosteroid positive modulator of GABAA receptors.The Journal of pharmacology and experimental therapeutics · 2006
- Androstenol, a putative human pheromone, affects human (Homo sapiens) male choice performance.Journal of comparative psychology (Washington, D.C. : 1983) · 1987
- Is 3alpha-androstenol pheromone related to menstrual synchrony?The journal of family planning and reproductive health care · 2007
- Comparative differential scanning calorimetric and FTIR and 31P-NMR spectroscopic studies of the effects of cholesterol and androstenol on the thermotropic phase behavior and organization of phosphatidylcholine bilayers.Biophysical journal · 1994
via PubMed
Wikidata facts
Show 3 more facts
- canonical SMILES
- CC12CCC3C(C1CC=C2)CCC4C3(CCC(C4)O)C
- chemical formula
- C₁₉H₃₀O
- isomeric SMILES
- C[C@]12CC[C@H]3[C@H]([C@@H]1CC=C2)CC[C@@H]4[C@@]3(CC[C@H](C4)O)C
Sources (2)
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Encyclopedic overview
5 sectionsContents
- Biosynthesis
- Distribution
- Biological activity
- See also
- References
Androstenol, also known as 5α-androst-16-en-3α-ol (shortened to 3α,5α-androstenol or 3α-androstenol), is a 16-androstene class steroidal pheromone and neurosteroid in humans and other mammals, notably pigs. It possesses a characteristic musk-like odor.
Androstenol, or a derivative, is found in black truffles. This was offered as an explanation for how pigs locate them deep in the ground: Androstenol is produced in the saliva of male pigs. However, experiments in France using pigs to scent truffles, truffle scent extract, and purified androstenol showed that pigs responded to the first two (actually trying to eat dirt containing the truffle extract), but ignored the androstenol.
Excerpted from Wikipedia’s “androstenol” article, available under the CC BY-SA 4.0 licence.