4-dimethylaminophenol

4-Dimethylaminophenol (DMAP) is an aromatic compound containing both phenol and amine functional groups. It has the molecular formula C8H11NO.

Chemical data

Formula: C8H11NO
Molecular weight: 137.18 g/mol
IUPAC name: 4-(dimethylamino)phenol
SMILES: CN(C)C1=CC=C(C=C1)O
InChIKey: JVVRCYWZTJLJSG-UHFFFAOYSA-N
XLogP: 2.1
Polar surface area: 23.5 Å²
H-bond donors: 1
H-bond acceptors: 2
Formal charge: 0

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Drug data · ChEMBL

Molecule type: Small molecule

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Research

86 papers

4-Dimethylaminophenol: A 'Smaller'-Molecule PPI Inhibitor Targeting the PSD95 GK Domain Against Ischemic Stroke.Angewandte Chemie (International ed. in English) · 2026
Biotransformation of 4-dimethylaminophenol in man.Archives of toxicology · 1981
Treatment of cyanide poisoning with 4-dimethylaminophenol (DMAP)--experimental and clinical overview.Fundamental and applied toxicology : official journal of the Society of Toxicology · 1983
Which cyanide antidote?Critical reviews in toxicology · 2009
Treatment of cyanide poisoning with 4-dimethylaminophenol (DMAP)--experimental and clinical overview.Middle East journal of anaesthesiology · 1990

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Wikidata facts

Subclass of: chemical compound
Mass: 137.084

Show 4 more facts

chemical formula: C₈H₁₁NO
canonical SMILES: CN(C)C1=CC=C(C=C1)O
subject has role: antidote
Commons category: 4-Dimethylaminophenol

Sources (2)

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Encyclopedic overview

3 sections

Contents

Uses
See also
References

4-Dimethylaminophenol (DMAP) is an aromatic compound containing both phenol and amine functional groups. It has the molecular formula C8H11NO.

==Uses== 4-Dimethylaminophenol has been used as an antidote for cyanide poisoning. It has also been shown to be effective in treating hydrogen sulfide toxicity.

Excerpted from Wikipedia’s “4-dimethylaminophenol” article, available under the CC BY-SA 4.0 licence.

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