Tyrosine-protein kinase HCK is an enzyme that in humans is encoded by the HCK gene.
Tyrosine-protein kinase HCK is an enzyme that in humans is encoded by the HCK gene.
== Structure == HCK comprises five distinct domains which include two terminal domains and three SH domains. The N-terminal domain is important for lipid modifications and a C-terminal domain includes a regulatory tyrosine residue. Next, HCK comprises three highly conserved SH domains: SH1, SH2, and SH3. The catalytic SH1 domain houses the kinase's active site. The regulatory SH3 and SH2 domains are tightly bound together when HCK is in an inactive state.
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).