Alfred G. Gilman

Alfred Goodman Gilman (July 1, 1941 – December 23, 2015) was an American pharmacologist and biochemist. He and Martin Rodbell shared the 1994 Nobel Prize in Physiology or Medicine "for their discovery of G-proteins and the role of these proteins in signal transduction in cells."

Gilman was the son of Alfred Gilman, who co-authored Goodman & Gilman's The Pharmacological Basis of Therapeutics with Louis S. Goodman, from whom his middle name came. He earned a BA in biology with major in biochemistry from Yale University. Immediately after graduation in 1962, he worked with Allan Conney at Burroughs Wellcome & Company, which resulted in the publication of his first two technical papers. Persuaded by Earl Wilbur Sutherland, Jr., he joined Case Western Reserve University School of Medicine for an MD–PhD course. He obtained his degree in 1969. He then went to the National Institutes of Health to work with Marshall Nirenberg between 1969 and 1971.