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alpha-amylase

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Also known as alpha-amylases

α-Amylase is an enzyme (; systematic name 4-α-D-glucan glucanohydrolase) that hydrolyses α bonds of large, α-linked polysaccharides, such as starch and glycogen, yielding shorter chains thereof, dextrins, and maltose, through the following biochemical process:

Key facts

Enzyme.Name
α-Amylase
Enzyme.EC_number
3.2.1.1
Enzyme.CAS_number
9000-90-2
Enzyme.image
Salivary alpha-amylase 1SMD.png
Enzyme.caption
Human salivary amylase: calcium ion visible in pale khaki, chloride ion in green. PDB
Protein family.Symbol
Alpha-amylase_C
Protein family.Name
Alpha amylase, C-terminal all-beta domain
Protein family.image
PDB 5cgt EBI.jpg
Protein family.caption
maltotriose complex of preconditioned cyclodextrin glycosyltransferase mutant
Protein family.Pfam
PF02806
Protein family.Pfam_clan
CL0369
Protein family.InterPro
IPR006048
Protein family.SCOP
1ppi
Protein family.OPM family
117
Protein family.OPM protein
1wza
Protein family.CAZy
GH13
Protein family.CDD
cd11338

via Wikipedia infobox

Research

21,376 papers

via PubMed

Wikidata facts

Show 2 more facts
EC enzyme number
3.2.1.1
Commons category
Alpha-Amylases
Sources (3)

via Wikidata · CC0

~8 min read

Article

18 sections
Contents
  • In human biology
  • Salivary amylase (ptyalin)
  • Optimum conditions for ptyalin
  • Genetic variation in human salivary amylase
  • Pancreatic amylase
  • In pathology
  • Interpretation
  • Genes
  • In grain
  • Industrial use
  • Potential for medical use
  • Disease and health relevance
  • Buffer inhibition
  • Determination
  • Domain architecture
  • See also
  • References
  • External links

α-Amylase is an enzyme (; systematic name 4-α-D-glucan glucanohydrolase) that hydrolyses α bonds of large, α-linked polysaccharides, such as starch and glycogen, yielding shorter chains thereof, dextrins, and maltose, through the following biochemical process: Endohydrolysis of (1→4)-α-D-glucosidic linkages in polysaccharides containing three or more (1→4)-α-linked D-glucose units

It is the major form of amylase found in humans and other mammals. It is also present in seeds containing starch as a food reserve, and is secreted by many fungi. It is a member of glycoside hydrolase family 13.

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