File:Polypeptide_forming_an_alpha_helix,_with_hydrogen_bonds_in_magenta.gif · Wikimedia Commons · See Wikimedia Commons
alpha helix
Sign in to saveAlso known as α-helix, Protein Conformation, alpha-Helical
type of secondary structure
Research
40,657 papers- α-Helix-Mediated Protein Adhesion.Journal of the American Chemical Society · 2023
- Exo-chirality of the α-helix.Nature communications · 2024
- Metal-α-Helix Peptide Frameworks.Journal of the American Chemical Society · 2025
- Discovery of α-helix-mimicking sulfono-γ-AApeptides as p53-MDM2 inhibitors.Future medicinal chemistry · 2021
- Conformationally Controlled sp(3) -Hydrocarbon-Based α-Helix Mimetics.Angewandte Chemie (International ed. in English) · 2023
via PubMed
~22 min read
Encyclopedic overview
Three-dimensional structure of an alpha helix in the protein crambin An alpha helix (or α-helix) is a sequence of amino acids in a protein that are twisted into a coil (a helix).
The alpha helix is the most common structural arrangement in the secondary structure of proteins. It is also the most extreme type of local structure, and it is the local structure that is most easily predicted from a sequence of amino acids.
Excerpted from Wikipedia’s “alpha helix” article, available under the CC BY-SA 4.0 licence.