ricin
Sign in to saveRicin ( ) is a lectin (a carbohydrate-binding protein) and a highly potent toxin produced in the seeds of the castor oil plant, Ricinus communis. The median lethal dose (LD50) of ricin for mice is around 22 micrograms per kilogram of body mass via intraperitoneal injection. Oral exposure to ricin is far less toxic. An estimated lethal oral dose in humans is approximately one milligram per kilogram of body mass.
Key facts
- Nonhuman protein.Name
- Ricin
- Nonhuman protein.image
- ricin structure.png
- Nonhuman protein.caption
- Ricin structure (). The A chain is shown in blue and the B chain in orange.
- Nonhuman protein.Organism
- Ricinus communis
- Nonhuman protein.TaxID
- 3988
- Nonhuman protein.Symbol
- RCOM_2159910
- Nonhuman protein.EntrezGene
- 8287993
- Nonhuman protein.RefSeqmRNA
- XM_002534603.1
- Nonhuman protein.RefSeqProtein
- XP_002534649.1
- Nonhuman protein.UniProt
- P02879
- Nonhuman protein.ECnumber
- 3.2.2.22
- Nonhuman protein.Chromosome
- whole genome
- Nonhuman protein.EntrezChromosome
- NW_002995687.1
- Nonhuman protein.GenLoc_start
- 3835
- Nonhuman protein.GenLoc_end
- 6287
- Protein family.Symbol
- N/A
- Protein family.Name
- Ricin-type beta-trefoil lectin domain (Ricin B chain)
- Protein family.Pfam
- PF00652
via Wikipedia infobox
Article
23 sectionsContents
- Biochemistry
- Biosynthesis
- Structure
- Entry into the cytoplasm
- Ribosome inactivation
- Depurination reaction
- Toxicity
- Symptoms
- Treatment
- Prevention
- Sources
- Therapeutic applications
- Regulation
- Chemical or biological warfare agent
- History
- Control
- Vaccination
- Synthesis
- Terrorist use
- In popular culture
- See also
- References
- External links
Ricin ( ) is a lectin (a carbohydrate-binding protein) and a highly potent toxin produced in the seeds of the castor oil plant, Ricinus communis. The median lethal dose (LD50) of ricin for mice is around 22 micrograms per kilogram of body mass via intraperitoneal injection. Oral exposure to ricin is far less toxic. An estimated lethal oral dose in humans is approximately one milligram per kilogram of body mass.
Ricin is a toxalbumin and was first described by Peter Hermann Stillmark, the founder of lectinology. Ricin is chemically similar to robin.