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Amanullin

Structure via PubChem · Public domain (PubChem)

EntityQ4739979· pop 11· linked from 198 articles

Also known as 3-Isoleucine-alpha-amanitin

Amanullin is a cyclic peptide. It is an amatoxin, all of which are found in several members of the mushroom genus Amanita. The oral of amanullin is approximately 20 mg/kg in mice; however, it is non-toxic in humans.

Chemical data

Formula
C39H54N10O12S
Molecular weight
887 g/mol
IUPAC name
2-[13,34-di(butan-2-yl)-8,22-dihydroxy-2,5,11,14,27,30,33,36,39-nonaoxo-27lambda4-thia-3,6,12,15,25,29,32,35,38-nonazapentacyclo[14.12.11.06,10.018,26.019,24]nonatriaconta-18(26),19(24),20,22-tetraen-4-yl]acetamide
SMILES
CCC(C)C1C(=O)NCC(=O)NC2CS(=O)C3=C(CC(C(=O)NCC(=O)N1)NC(=O)C(NC(=O)C4CC(CN4C(=O)C(NC2=O)CC(=O)N)O)C(C)CC)C5=C(N3)C=C(C=C5)O
InChIKey
QQLVIKWYAVVKKF-UHFFFAOYSA-N
XLogP
-2.2
Polar surface area
360 Ų
H-bond donors
11
H-bond acceptors
13
Formal charge
0

via PubChem

Wikidata facts

Mass
886.364338
Show 2 more facts
chemical formula
C₃₉H₅₄N₁₀O₁₂S
canonical SMILES
CCC(C)C1C(=O)NCC(=O)NC2CS(=O)C3=C(CC(C(=O)NCC(=O)N1)NC(=O)C(NC(=O)C4CC(CN4C(=O)C(NC2=O)CC(=O)N)O)C(C)CC)C5=C(N3)C=C(C=C5)O
Sources (1)

via Wikidata · CC0

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Encyclopedic overview

4 sections
Contents
  • Toxicology
  • See also
  • References
  • External links

Amanullin is a cyclic peptide. It is an amatoxin, all of which are found in several members of the mushroom genus Amanita. The oral of amanullin is approximately 20 mg/kg in mice; however, it is non-toxic in humans.

==Toxicology==

Excerpted from Wikipedia’s “Amanullin” article, available under the CC BY-SA 4.0 licence.

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