Structure via PubChem · Public domain (PubChem)
ampicillin/flucloxacillin
Sign in to saveAlso known as co-fluampicil, Magnapen
Ampicillin/flucloxacillin (INNs) also known as co-fluampicil (BAN), and sold under the tradename Magnapen, is a combination drug of the two β-lactam antibiotics, ampicillin and flucloxacillin, both in equal amounts, available in a capsule and as a liquid, both taken by mouth, and as a formulation which can be given by injection into muscle or vein.
In the Vinony graph
Vinony's link graph records 186 inbound references to ampicillin/flucloxacillin, and connects out to intravenous infusion and defusion, β-lactam antibiotic and amoxicillin/clavulanic acid.
It is catalogued under topics including Chemical articles with multiple CAS registry numbers, Chemical pages without DrugBank identifier and Combination antibiotics.
Vinony links it to 5 Wikipedia language editions.
Chemical data
- Formula
- C35H36ClFN6O9S2
- Molecular weight
- 803.3 g/mol
- IUPAC name
- (2S,5R,6R)-6-[[(2S)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;(2S,5R,6R)-6-[[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
- SMILES
- CC1=C(C(=NO1)C2=C(C=CC=C2Cl)F)C(=O)N[C@H]3[C@@H]4N(C3=O)[C@H](C(S4)(C)C)C(=O)O.CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@H](C3=CC=CC=C3)N)C(=O)O)C
- InChIKey
- MRHKOEQOYWPVKY-LGHZNYKCSA-N
- Polar surface area
- 276 Ų
- H-bond donors
- 5
- H-bond acceptors
- 14
- Formal charge
- 0
via PubChem
Wikidata facts
- Subclass of
- combination drug
- Has part
- flucloxacillin
Show 1 more fact
- isomeric SMILES
- CC1(C)S[C@@H]2[C@H](N=C(O)[C@@H](N)c3ccccc3)C(=O)N2[C@H]1C(=O)O.Cc1onc(-c2c(F)cccc2Cl)c1C(O)=N[C@@H]1C(=O)N2[C@@H]1SC(C)(C)[C@@H]2C(=O)O
via Wikidata · CC0
~3 min read
Encyclopedic overview
9 sectionsContents
- Indication
- Formulations
- Dosage
- Side effects and contraindications
- Interactions
- Pregnancy and breastfeeding
- History
- See also
- References
Ampicillin/flucloxacillin (INNs) also known as co-fluampicil (BAN), and sold under the tradename Magnapen, is a combination drug of the two β-lactam antibiotics, ampicillin and flucloxacillin, both in equal amounts, available in a capsule and as a liquid, both taken by mouth, and as a formulation which can be given by injection into muscle or vein.
It is used to treat infections before the laboratory results confirm the causative organism. Side effects include stomach or bowel upsets. It should not be taken by people allergic to penicillin.
Excerpted from Wikipedia’s “ampicillin/flucloxacillin” article, available under the CC BY-SA 4.0 licence.