Carbenicillin is a bactericidal antibiotic belonging to the carboxypenicillin subgroup of the penicillins. It was discovered by scientists at Beecham and marketed as Pyopen. It has Gram-negative coverage which includes Pseudomonas aeruginosa but limited Gram-positive coverage. The carboxypenicillins are susceptible to degradation by beta-lactamase enzymes, although they are more resistant than ampicillin to degradation. Carbenicillin is also more stable at lower pH than ampicillin.
via PubMed
{{Drugbox | Verifiedfields = changed | verifiedrevid = 460017669 | IUPAC_name = (2S,5R,6R)-6-{[carboxy(phenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid | image = Carbenicillin.svg | image_class = skin-invert-image | synonyms = CB
| tradename = Geocillin; Pyopen | Drugs.com = | pregnancy_US = B | pregnancy_category = Passes into breast milk | legal_status= Rx-only | routes_of_administration = Oral, parenteral
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).