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cephaloridine

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Also known as 40602, Kefloridin, Cephalomycine, cefaloridine, (6R,7R)-8-oxo-3-(pyridin-1-ium-1-ylmethyl)- 7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1- azabicyclo[4.2.0]oct-2-ene-2-carboxylate, Loridine, (6R,7R)-8-oxo-3-(pyridinium-1-ylmethyl)-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate, N-(7-(2'-Thienylacetamidoceph-3-ylmethyl))-pyridinium-2-carboxylate

Cephaloridine (or cefaloridine) is a first-generation semisynthetic derivative of antibiotic cephalosporin C. It is a Beta lactam antibiotic, like penicillin. Its chemical structure contains cephems,carboxyl groups and a pyridinium ring.

Research

7,492 papers

via PubMed

~11 min read

Encyclopedic overview

17 sections
Contents
  • History
  • Structure & reactivity
  • Synthesis
  • Clinical use of cephaloridine
  • Kinetics
  • Absorption
  • Distribution
  • Pregnancy
  • Metabolism and excretion
  • Pharmacokinetics
  • Adverse effects
  • Toxicity
  • Metabolism
  • Symptoms of kidney damage caused by cephaloridine
  • Complications caused by cephaloridine
  • Treatment of kidney damage caused by cephaloridine
  • References

Cephaloridine (or cefaloridine) is a first-generation semisynthetic derivative of antibiotic cephalosporin C. It is a Beta lactam antibiotic, like penicillin. Its chemical structure contains cephems,carboxyl groups and a pyridinium ring.

Cephaloridine is mainly used in veterinary practice. It is unique among cephalosporins in that it exists as a zwitterion.

Excerpted from Wikipedia’s “cephaloridine” article, available under the CC BY-SA 4.0 licence.