Structure via PubChem · Public domain (PubChem)
anserine
Sign in to saveAlso known as beta-alanyl-3-methyl-L-histidine, L-Anserine, (2S)-2-(3-aminopropanamido)-3-(1-methyl-1H-imidazol-5-yl)propanoic acid, L-N-beta-Alanyl-3-methyl-Histidine, beta-Alanyl-N(pai)-methyl-L-histidine, N-b-Alanyl-3-methyl-L-Histidine, L-N-b-Alanyl-3-methyl-Histidine, N-beta-Alanyl-3-methyl-L-histidine
Anserine (β-alanyl-3-methylhistidine) is a dipeptide containing β-alanine and 3-methylhistidine. Anserine is a derivative of carnosine, which has been methylated.
Chemical data
- Formula
- C10H16N4O3
- Molecular weight
- 240.26 g/mol
- IUPAC name
- (2S)-2-(3-aminopropanoylamino)-3-(3-methylimidazol-4-yl)propanoic acid
- SMILES
- CN1C=NC=C1C[C@@H](C(=O)O)NC(=O)CCN
- InChIKey
- MYYIAHXIVFADCU-QMMMGPOBSA-N
- XLogP
- -4
- Polar surface area
- 110 Ų
- H-bond donors
- 3
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
905 papers- Pes Anserine Bursitis.2026
- Anserine syndrome.Revista brasileira de reumatologia · 2010
- An update on carnosine and anserine research.Amino acids · 2019
- Anserine, Balenine, and Ergothioneine: Impact of Histidine-Containing Compounds on Exercise Performance-A Narrative Review.Nutrients · 2025
- Traumatic Anserine Folliculosis.Indian pediatrics · 2020
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Part of
- chicken as food
- Has part
- oxygen
- Mass
- 240.12224
Show 5 more facts
- chemical formula
- C₁₀H₁₆N₄O₃
- canonical SMILES
- CN1C=NC=C1CC(C(=O)O)NC(=O)CCN
- isomeric SMILES
- CN1C=NC=C1C[C@@H](C(=O)O)NC(=O)CCN
- found in taxon
- Caenorhabditis elegans
- Commons category
- Anserine
via Wikidata · CC0
~1 min read
Encyclopedic overview
5 sectionsContents
- Biosynthesis
- Anti-inflammatory effects
- Metal binding
- See also
- References
Anserine (β-alanyl-3-methylhistidine) is a dipeptide containing β-alanine and 3-methylhistidine. Anserine is a derivative of carnosine, which has been methylated.
Anserine has biological activities similar to those of carnosine, including buffering activity, antioxidant properties, metal ion chelation, and anti-aggregation effects. Both anserine and carnosine chelate copper. Because of its methylation, anserine is more stable in serum and resistant to degradation than carnosine. Compared with carnosine, anserine have a higher antioxidant capacity.
Excerpted from Wikipedia’s “anserine” article, available under the CC BY-SA 4.0 licence.