arecaidine
Sign in to saveArecaidine, also known as '''N-methylguvacine''', is an alkaloid in areca nuts and a GABA reuptake inhibitor. It is structurally similar to the GABA reuptake inhibitors guvacine and nipecotic acid. Arecaidine has been found to produce sedative effects in mice and to protect against the lethality of the GABAA receptor antagonists bicuculline and pentylenetetrazol. On the other hand, it did not produce anticonvulsant effects. Lime is said to hydrolyse arecoline to arecaidine.
Key facts
- Drug.image
- Arecaidine.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 175px
- Drug.class
- GABA reuptake inhibitor; Sedative
- Drug.ATC_prefix
- None
- Drug.CAS_number
- 499-04-7
- Drug.PubChem
- 10355
- Drug.IUPHAR_ligand
- 9487
- Drug.ChemSpiderID
- 9928
- Drug.UNII
- 0S8YEV0D4O
- Drug.KEGG
- C10128
- Drug.ChEBI
- 2813
- Drug.ChEMBL
- 432561
- Drug.synonyms
- Methylguvacine; Arecaine; N-Methylguvacine
- Drug.IUPAC_name
- 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylic acid
- Drug.C
- 7
- Drug.H
- 11
- Drug.N
- 1
via Wikipedia infobox
Wikidata facts
- Mass
- 141.079
Show 3 more facts
- chemical formula
- C₇H₁₁NO₂
- canonical SMILES
- CN1CCC=C(C1)C(=O)O
- Commons category
- Arecaidine
Sources (2)
via Wikidata · CC0
~1 min read
Article
1 sectionsContents
- References
Arecaidine, also known as '''N-methylguvacine''', is an alkaloid in areca nuts and a GABA reuptake inhibitor. It is structurally similar to the GABA reuptake inhibitors guvacine and nipecotic acid. Arecaidine has been found to produce sedative effects in mice and to protect against the lethality of the GABAA receptor antagonists bicuculline and pentylenetetrazol. On the other hand, it did not produce anticonvulsant effects. Lime is said to hydrolyse arecoline to arecaidine.
== References ==