SLC6A1
Sign in to saveAlso known as GABATHG, GABATR, GAT1, MAE, GABA transporter 1, solute carrier family 6 member 1
protein-coding gene in the species Homo sapiens
Gene data
SLC6A1- Name
- solute carrier family 6 member 1
- Type
- protein-coding
- Position
- 10,992,177–11,039,247 (+)
- Aliases
- GABATHG, GABATR, GAT1, MAE, hGAT-1
- Ensembl
- ENSG00000157103
- RefSeq RNA
- NM_001348250.2, NM_001348251.2, NM_001348252.2, NM_001348253.2, NM_003042.4
- RefSeq protein
- NP_001335179.1, NP_001335180.1, NP_001335181.1, NP_001335182.1, NP_003033.3
The protein encoded by this gene is a gamma-aminobutyric acid (GABA) transporter that localizes to the plasma membrane. The encoded protein removes GABA from the synaptic cleft, restoring it to presynaptic terminals. [provided by RefSeq, Jan 2017].
Gene Ontology
Biological process
Molecular function
amino acid:sodium symporter activitygamma-aminobutyric acid:sodium:chloride symporter activitygamma-aminobutyric acid:sodium:chloride symporter activitygamma-aminobutyric acid:sodium:chloride symporter activitygamma-aminobutyric acid:sodium:chloride symporter activitygamma-aminobutyric acid:sodium:chloride symporter activityprotein bindinggamma-aminobutyric acid transmembrane transporter activity
Pathways
Synaptic vesicle cycle - Homo sapiens (human)GABAergic synapse - Homo sapiens (human)Neurotransmitter release cycleTransmission across Chemical SynapsesNeuronal SystemTransport of small moleculesSLC-mediated transmembrane transportSLC-mediated transport of neurotransmittersGABA synthesis, release, reuptake and degradationReuptake of GABA
via MyGene.info
Gene · Ensembl
solute carrier family 6 member 1
- Symbol
- SLC6A1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 3:10,992,177-11,039,247
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 9 more facts
- HomoloGene ID
- 2290
- genetic association
- conduct disorder
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/6529
- chromosome
- human chromosome 3
- genomic start
- 10992186
- genomic end
- 11039247
- cytogenetic location
- 3p25.3
- expressed in
- caudate nucleus
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