Structure via PubChem · Public domain (PubChem)
atazanavir
Sign in to saveAlso known as CGP-73547, ATZ, ATV, Zrivada, Latazanavir, Atazanavirum
Atazanavir, sold under the brand name Reyataz among others, is an antiretroviral medication used to treat HIV/AIDS. It is generally recommended for use with other antiretrovirals. It may be used for post-exposure prophylaxis after a needlestick injury or other potential exposure. It is taken by mouth.
Chemical data
- Formula
- C38H52N6O7
- Molecular weight
- 704.9 g/mol
- IUPAC name
- methyl N-[(2S)-1-[2-[(2S,3S)-2-hydroxy-3-[[(2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoyl]amino]-4-phenylbutyl]-2-[(4-pyridin-2-ylphenyl)methyl]hydrazinyl]-3,3-dimethyl-1-oxobutan-2-yl]carbamate
- SMILES
- CC(C)(C)[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)[C@H](CN(CC2=CC=C(C=C2)C3=CC=CC=N3)NC(=O)[C@H](C(C)(C)C)NC(=O)OC)O)NC(=O)OC
- InChIKey
- AXRYRYVKAWYZBR-GASGPIRDSA-N
- XLogP
- 5.6
- Polar surface area
- 171 Ų
- H-bond donors
- 5
- H-bond acceptors
- 9
- Formal charge
- 0
via PubChem
~7 min read
Encyclopedic overview
7 sectionsContents
- Medical uses
- Pregnancy
- Contraindications
- Adverse effects
- Mechanism of action
- Synthesis
- References
{{Drugbox | Verifiedfields = changed | verifiedrevid = 458476502 | image = Atazanavir structure.svg | image_class = skin-invert-image | width = 180 | alt = | image2 = Atazanavir ball-and-stick.png | image_class2 = bg-transparent | width2 = 220 | alt2 =
| pronounce = | tradename = Reyataz, Evotaz, others | Drugs.com = | MedlinePlus = a603019 | DailyMedID = Atazanavir | pregnancy_AU = B2 | pregnancy_AU_comment = | routes_of_administration = By mouth | ATC_prefix = J05 | ATC_suffix = AE08 | ATC_supplemental =
Excerpted from Wikipedia’s “atazanavir” article, available under the CC BY-SA 4.0 licence.