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Structure via PubChem · Public domain (PubChem)
atevirdine
Sign in to saveAtevirdine is a non-nucleoside reverse transcriptase inhibitor that has been studied for the treatment of HIV.
Chemical data
- Formula
- C21H25N5O2
- Molecular weight
- 379.5 g/mol
- IUPAC name
- [4-[3-(ethylamino)-2-pyridinyl]piperazin-1-yl]-(5-methoxy-1H-indol-2-yl)methanone
- SMILES
- CCNC1=C(N=CC=C1)N2CCN(CC2)C(=O)C3=CC4=C(N3)C=CC(=C4)OC
- InChIKey
- UCPOMLWZWRTIAA-UHFFFAOYSA-N
- XLogP
- 3
- Polar surface area
- 73.5 Ų
- H-bond donors
- 2
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- HIV infection
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 379.201
Show 4 more facts
- chemical formula
- C₂₁H₂₅N₅O₂
- canonical SMILES
- CCNC1=C(N=CC=C1)N2CCN(CC2)C(=O)C3=CC4=C(N3)C=CC(=C4)OC
- subject has role
- reverse-transcriptase inhibitor
- Commons category
- Atevirdine
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Synthesis
- See also
- References
Atevirdine is a non-nucleoside reverse transcriptase inhibitor that has been studied for the treatment of HIV.
==Synthesis== thumb|center|500px|class=skin-invert-image|Atevirdine synthesis: Structure-activity relationship|SAR:
Excerpted from Wikipedia’s “atevirdine” article, available under the CC BY-SA 4.0 licence.