ATP1A2

Name

ATPase Na+/K+ transporting subunit alpha 2

Type

protein-coding

Position

160,115,755–160,143,605 (+)

Aliases

DEE98, FARIMPD, FHM2, MHP2

Ensembl

ENSG00000018625

RefSeq RNA

NM_000702.4, XM_047421286.1, XM_054336759.1

RefSeq protein

NP_000693.1, XP_047277242.1, XP_054192734.1

The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 2 subunit. Mutations in this gene result in familial basilar or hemiplegic migraines, and in a rare syndrome known as alternating hemiplegia of childhood. [provided by RefSeq, Oct 2008].

via MyGene.info

Gene · Ensembl

ATPase Na+/K+ transporting subunit alpha 2

Symbol

ATP1A2

Biotype

Protein coding

Organism

Homo sapiens

Location

1:160,115,755-160,143,605

Strand

Forward (+)

Assembly

GRCh38