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باربیژرون

Structure via PubChem · Public domain (PubChem)

EntityQ4859690· pop 7· linked from 38 articles

باربیژرون

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Barbigerone is one of a few pyranoisoflavones among several groups of isoflavones. It was first isolated from the seed of a leguminous plant Tephrosia barbigera; hence the name "barbigerone". Members of the genus Millettia are now known to be rich in barbigerone, including M. dielsiena, M. ferruginea, M. usaramensis, and M. pachycarpa. It has also been isolated from the medicinal plant Sarcolobus globosus. Barbigerone from S. globosus is validated to have significant antioxidant property. Barbigerone exhibits profound antiplasmodial activity against the malarial parasite Plasmodium falciparum.

Chemical data

Formula
C23H22O6
Molecular weight
394.4 g/mol
IUPAC name
8,8-dimethyl-3-(2,4,5-trimethoxyphenyl)pyrano[2,3-f]chromen-4-one
SMILES
CC1(C=CC2=C(O1)C=CC3=C2OC=C(C3=O)C4=CC(=C(C=C4OC)OC)OC)C
InChIKey
OBIUGMGQVQMVSK-UHFFFAOYSA-N
XLogP
4
Polar surface area
63.2 Ų
H-bond donors
0
H-bond acceptors
6
Formal charge
0

via PubChem

Drug data · ChEMBL

Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Mass
394.141638
Show 4 more facts
Commons category
Barbigerone
found in taxon
Tephrosia nana
chemical formula
C₂₃H₂₂O₆
canonical SMILES
CC1(C=CC2=C(O1)C=CC3=C2OC=C(C3=O)C4=CC(=C(C=C4OC)OC)OC)C
Sources (3)

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