
daidzein
Sign in to saveAlso known as 7,4'-dihydroxyisoflavone, 4',7-dihydroxy-Isoflavone, 7-hydroxy-3-(4-hydroxyphenyl)-4-benzopyrone, 7-hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, 4',7-dihydroxyisoflavone, daidzeol, isoaurostatin
Daidzein (7-hydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one) is a naturally occurring compound found exclusively in soybeans and other legumes, and structurally belongs to a class of compounds known as isoflavones. Daidzein and other isoflavones are produced in plants through the phenylpropanoid pathway of secondary metabolism and are used as signal carriers, and defense responses to pathogenic attacks. Upon consumption of isoflavone-rich foods, daidzein has poor bioavailability and low water solubility.
Research
4,744 papers- Liberation of daidzein by gut microbial β-galactosidase suppresses acetaminophen-induced hepatotoxicity in mice.Cell host & microbe · 2023
- Daidzein and its Effects on Brain.Current medicinal chemistry · 2017
- Bioflavonoid Daidzein: Therapeutic Insights, Formulation Advances, and Future Directions.Drug research · 2024
- Unlocking daidzein's healing power: Present applications and future possibilities in phytomedicine.Phytomedicine : international journal of phytotherapy and phytopharmacology · 2024
- Daidzein's potential in halting neurodegeneration: unveiling mechanistic insights.Naunyn-Schmiedeberg's archives of pharmacology · 2025
via PubMed
Wikidata facts
- Mass
- 254.058
Show 3 more facts
- chemical formula
- C₁₅H₁₀O₄
- canonical SMILES
- C1=CC(=CC=C1C2=COC3=C(C2=O)C=CC(=C3)O)O
- Commons category
- Daidzein
via Wikidata · CC0
~4 min read
Article
10 sectionsContents
- Natural occurrence
- Biosynthesis
- History
- Pathway
- Research
- Pathogen interactions
- Derivatives
- Glycosides
- Plants containing daidzein
- References
Daidzein (7-hydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one) is a naturally occurring compound found exclusively in soybeans and other legumes, and structurally belongs to a class of compounds known as isoflavones. Daidzein and other isoflavones are produced in plants through the phenylpropanoid pathway of secondary metabolism and are used as signal carriers, and defense responses to pathogenic attacks. Upon consumption of isoflavone-rich foods, daidzein has poor bioavailability and low water solubility.
==Natural occurrence== Daidzein and other isoflavone compounds, such as genistein, are present in a number of plants and herbs like kwao krua (Pueraria mirifica) and kudzu. It can also be found in Maackia amurensis cell cultures. Daidzein can be found in food such as mature soybeans and soy products like soy protein concentrate, tofu and textured vegetable protein.