Structure via PubChem · Public domain (PubChem)
ipriflavone
Sign in to saveAlso known as FL-113, 7-isopropoxyisoflavone, 7-(1-methylethoxy)-3-phenyl-4H-1-benzopyran-4-one
Ipriflavone (INN, JAN; brand name Yambolap) is a synthetic isoflavone which may be used to inhibit bone resorption, maintain bone density and to prevent osteoporosis in postmenopausal women. It is not used to treat osteoporosis. It slows down the action of the osteoclasts (bone-eroding cells), possibly allowing the osteoblasts (bone-building cells) to build up bone mass.
Chemical data
- Formula
- C18H16O3
- Molecular weight
- 280.3 g/mol
- IUPAC name
- 3-phenyl-7-propan-2-yloxychromen-4-one
- SMILES
- CC(C)OC1=CC2=C(C=C1)C(=O)C(=CO2)C3=CC=CC=C3
- InChIKey
- SFBODOKJTYAUCM-UHFFFAOYSA-N
- XLogP
- 4
- Polar surface area
- 35.5 Ų
- H-bond donors
- 0
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- bone disease
via ChEMBL · EBI
Wikidata facts
- Subclass of
- isoflavone
- Mass
- 280.11
Show 3 more facts
- chemical formula
- C₁₈H₁₆O₃
- canonical SMILES
- CC(C)OC1=CC2=C(C=C1)C(=O)C(=CO2)C3=CC=CC=C3
- World Health Organisation international non-proprietary name
- ipriflavone
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- External links
Ipriflavone (INN, JAN; brand name Yambolap) is a synthetic isoflavone which may be used to inhibit bone resorption, maintain bone density and to prevent osteoporosis in postmenopausal women. It is not used to treat osteoporosis. It slows down the action of the osteoclasts (bone-eroding cells), possibly allowing the osteoblasts (bone-building cells) to build up bone mass.
A clinical trial reported in 2001 that it was not effective in prevention or treatment of osteoporosis.
Excerpted from Wikipedia’s “ipriflavone” article, available under the CC BY-SA 4.0 licence.
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via Wikidata sitelinks · CC0