benfotiamine
Sign in to saveBenfotiamine (rINN, or '''S-benzoylthiamine O-monophosphate') is a synthetic, fat-soluble, S''-acyl derivative of thiamine (vitamin B1) that is approved in some countries as a medication or dietary supplement to treat diabetic sensorimotor polyneuropathy. Benfotiamine was developed in the late 1950s in Japan.
Research
268 papers- Benfotiamine and Cognitive Decline in Alzheimer's Disease: Results of a Randomized Placebo-Controlled Phase IIa Clinical Trial.Journal of Alzheimer's disease : JAD · 2020
- Thiamine and benfotiamine: Focus on their therapeutic potential.Heliyon · 2023
- Potential of Benfotiamine in the treatment of neuropsychological disorders.Molecular biology reports · 2025
- Benfotiamine Reduces Dendritic Cell Inflammatory Potency.Endocrine, metabolic & immune disorders drug targets · 2021
- Therapeutic potential of benfotiamine and its molecular targets.European review for medical and pharmacological sciences · 2018
via PubMed
Wikidata facts
- Mass
- 466.107592
Show 4 more facts
- chemical formula
- C₁₉H₂₃N₄O₆PS
- canonical SMILES
- CC1=NC=C(C(=N1)N)CN(C=O)C(=C(CCOP(=O)(O)O)SC(=O)C2=CC=CC=C2)C
- Commons category
- Benfotiamine
- isomeric SMILES
- C/C(=C(\CCOP(=O)(O)O)SC(=O)c1ccccc1)N(C=O)Cc1cnc(C)[nH]c1=N
Sources (1)
via Wikidata · CC0
~4 min read
Article
7 sectionsContents
- Uses
- Adverse effects
- Pharmacology
- Chemistry
- Research
- See also
- References
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| Drugs.com = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = OTC | routes_of_administration = Oral