beta-galactosidase
Sign in to saveβ-Galactosidase (EC 3.2.1.23, beta-gal or β-gal; systematic name β-D-galactoside galactohydrolase) is a glycoside hydrolase enzyme that catalyzes hydrolysis of terminal non-reducing β-D-galactose residues in β-D-galactosides. (This enzyme digests many β-Galactosides, not just lactose. It is sometimes loosely referred to as lactase but that name is generally reserved for mammalian digestive enzymes that break down lactose specifically.)
Key facts
- Enzyme.Name
- β-Galactosidase
- Enzyme.EC_number
- 3.2.1.23
- Enzyme.CAS_number
- 9031-11-2
- Enzyme.GO_code
- 0009341
- Enzyme.image
- Beta-galactosidase (1tg7).png
- Enzyme.caption
- β-galactosidase from Penicillium sp. (from PDB )
- Enzyme.name
- β-Galactosidase
- Protein.Name
- galactosidase, beta 1
- Protein.HGNCid
- 4298
- Protein.Symbol
- GLB1
- Protein.AltSymbols
- ELNR1
- Protein.EntrezGene
- 2720
- Protein.OMIM
- 230500
- Protein.RefSeq
- NM_000404
- Protein.UniProt
- P16278
- Protein.Chromosome
- 3
- Protein.Arm
- p
- Protein.Band
- 22.3
via Wikipedia infobox
Research
38,696 papers- Senescence-associated beta-galactosidase is lysosomal beta-galactosidase.Aging cell · 2006
- β-Galactosidase.Cold Spring Harbor protocols · 2017
- Pharmacological Chaperones for β-Galactosidase Related to G(M1) -Gangliosidosis and Morquio B: Recent Advances.Chemical record (New York, N.Y.) · 2021
- Galantase (beta-galactosidase) treatment in pediatric practice.Therapia Hungarica (English edition) · 1989
- β-Galactosidase from Exiguobacterium acetylicum: Cloning, expression, purification and characterization.Bioresource technology · 2019
via PubMed
Article
8 sectionsContents
- Function
- Structure
- Reaction
- Applications
- Evolution
- Species distribution
- References
- External links
β-Galactosidase (EC 3.2.1.23, beta-gal or β-gal; systematic name β-D-galactoside galactohydrolase) is a glycoside hydrolase enzyme that catalyzes hydrolysis of terminal non-reducing β-D-galactose residues in β-D-galactosides. (This enzyme digests many β-Galactosides, not just lactose. It is sometimes loosely referred to as lactase but that name is generally reserved for mammalian digestive enzymes that break down lactose specifically.)
β-Galactosides include carbohydrates containing galactose where the glycosidic bond lies above the galactose molecule. Substrates of different β-galactosidases include ganglioside GM1, lactosylceramides, lactose, and various glycoproteins.