Arylsulfatase A

Protein · UniProt

Arylsulfatase A

Gene

ARSA

Organism

Homo sapiens (Human)

Length

507 aa

Molecular mass

53,588 Da

Evidence

1: Evidence at protein level

Lysosomal enzyme that catalyzes the hydrolysis of cerebroside-3-sulfate (sulfatide) into cerebroside and sulfate, a reaction that requires the activator protein saposin B

• PHASE1/PHASE2COMPLETED
  A Safety and Dose Ranging Study of Idursulfase (Intrathecal) Administration Via an Intrathecal Drug Delivery Device in Pediatric Patients With Hunter Syndrome Who Have Central Nervous System Involvement and Are Receiving Treatment With Elaprase®Shire · NCT00920647
• PHASE1/PHASE2COMPLETED
  Long-term Metazym Treatment of Patients With Late Infantile Metachromatic Leukodystrophy (MLD)Shire · NCT00633139
• PHASE1/PHASE2COMPLETED
  A Study to Evaluate the Safety, Tolerability and Efficacy of BMN 110 in Subjects With Mucopolysaccharidosis IVABioMarin Pharmaceutical · NCT00884949
• PHASE2COMPLETED
  PGL2001 Proof of Concept Study in Symptomatic EndometriosisPregLem SA · NCT01631981
• PHASE1COMPLETED
  Safety and Dose Ranging Study of Insulin Receptor MoAb-IDS Fusion Protein in Patients With Hunter SyndromeArmaGen, Inc · NCT02262338
• PHASE2COMPLETED
  Study of BMN 110 in Pediatric Patients < 5 Years of Age With Mucopolysaccharidosis IVA (Morquio A Syndrome)BioMarin Pharmaceutical · NCT01515956

via ClinicalTrials.gov

Wikidata facts

Instance of

protein

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