Also known as DSPG1, PG-S1, PGI, SLRR1A, biglycan, SEMDX, MRLS
gene umano
Gene data
BGN- Name
- biglycan
- Type
- protein-coding
- Chromosome
- X
- Position
- 153,488,654–153,510,711 (+)
- Aliases
- DSPG1, MRLS, PG-S1, PGI, SEMDX, SLRR1A
- Ensembl
- ENSG00000182492
- RefSeq RNA
- NM_001711.6, XM_017029724.3, XM_054327563.1
- RefSeq protein
- NP_001702.1, XP_016885213.1, XP_054183538.1
This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in bone growth, muscle development and regeneration, and collagen fibril assembly in multiple tissues. This protein may also regulate inflammation and innate immunity. Additionally, the encoded protein may contribute to atherosclerosis and aortic valve stenosis in human patients. This gene and the related gene decorin are thought to be the result of a gene duplication. [provided by RefSeq, Nov 2015].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
biglycan
- Symbol
- BGN
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- Chr X:153,488,654-153,510,711
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein BGN PDB 2ft3.png
Show 8 more facts
- HomoloGene ID
- 1293
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/633
- chromosome
- human X chromosome
- genomic start
- 153494980
- genomic end
- 153509546
- cytogenetic location
- Xq28
- expressed in
- gallbladder
Sources (7)
via Wikidata · CC0