Mucin 16, cell surface associated
Mucin-16 (MUC-16) also known as Ovarian cancer-related tumor marker CA125 is a protein that in humans is encoded by the MUC16 gene. MUC-16 is a member of the mucin family glycoproteins. MUC-16 has found application as a tumor marker or biomarker that may be elevated in the blood of some patients with specific types of cancers, most notably ovarian cancer, or other conditions that are benign.
Research
112 papers- Biomarkers of ocular allergy and dry eye disease.Romanian journal of ophthalmology · 2023
- Mucin 16 (cancer antigen 125) expression in human tissues and cell lines and correlation with clinical outcome in adenocarcinomas of the pancreas, esophagus, stomach, and colon.Human pathology · 2012
- Tumour extracellular vesicle surface Protein-mRNA integration assay for early detection of epithelial ovarian cancer.EBioMedicine · 2025
- Quantification of MUCIN 1, cell surface associated and MUCIN16, cell surface associated proteins in tears and conjunctival epithelial cells collected from postmenopausal women.Molecular vision · 2013
- Graft Versus Host Disease-Associated Dry Eye: Role of Ocular Surface Mucins and the Effect of Rebamipide, a Mucin Secretagogue.Investigative ophthalmology & visual science · 2019
via PubMed
Article
10 sectionsContents
- Structure
- Function
- Role in cancer
- As a biomarker
- Metastatic invasion
- Induced motility
- Chemotherapy resistance
- Discovery
- References
- External links
Mucin-16 (MUC-16) also known as Ovarian cancer-related tumor marker CA125 is a protein that in humans is encoded by the MUC16 gene. MUC-16 is a member of the mucin family glycoproteins. MUC-16 has found application as a tumor marker or biomarker that may be elevated in the blood of some patients with specific types of cancers, most notably ovarian cancer, or other conditions that are benign.
== Structure ==