mucin 1, cell surface associated

Protein · UniProt

Mucin-1

Gene

MUC1

Organism

Homo sapiens (Human)

Length

1,255 aa

Molecular mass

122,102 Da

Evidence

1: Evidence at protein level

The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack

• Targeting the cancer glycocalyx in salivary duct carcinoma: tumor-associated mucin 1 (Tn-MUC1) as a novel cell surface marker.The journal of pathology. Clinical research · 2025
• The endometrial cell surface and implantation. Expression of the polymorphic mucin MUC-1 and adhesion molecules during the endometrial cycle.Annals of the New York Academy of Sciences · 1994
• Cell surface-associated mucins in signal transduction.Trends in cell biology · 2006
• Quantification of MUCIN 1, cell surface associated and MUCIN16, cell surface associated proteins in tears and conjunctival epithelial cells collected from postmenopausal women.Molecular vision · 2013
• The cell surface mucin MUC1 limits the severity of influenza A virus infection.Mucosal immunology · 2017

via PubMed

• PHASE1COMPLETED
  Vaccine Therapy in Treating Patients With Metastatic Breast CancerDana-Farber Cancer Institute · NCT00003761
• PHASE1UNKNOWN
  Clinical Safety and Preliminary Efficacy of MUC1-DC-CTL Treatment in Stage IV Gastric Cancer.Beijing Doing Biomedical Co., Ltd. · NCT02602249
• PHASE1TERMINATED
  Vaccine Therapy in Treating Patients With Metastatic Breast CancerNational Cancer Institute (NCI) · NCT00071942

via ClinicalTrials.gov

Wikidata facts

Instance of

protein

via Wikidata · CC0