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bisphosphonate
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bisphosphonate

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Also known as diphosphonate, diphosphonates, biphosphonate, bisphosphonates, biphosphonates

thumb|200x200px|The general chemical structure of bisphosphonate. The Substituent|R-groups determine the chemical properties of the drug, and distinguishes individual types of bisphosphonates. This chemical structure affords a high affinity for calcium hydroxyapatite, allowing for rapid and specific skeletal targeting.

Research

39,564 papers

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Encyclopedic overview

17 sections
Contents
  • Chemical structure and mechanistic aspects
  • Medical uses
  • Post-menopausal osteoporosis
  • Cancer
  • Other
  • Adverse effects
  • Common
  • Long-term risks
  • Chemistry and classes
  • Pharmacokinetics
  • Mechanism of action
  • Non-nitrogenous
  • Nitrogenous
  • History
  • Notes
  • References
  • External links

thumb|200x200px|The general chemical structure of bisphosphonate. The Substituent|R-groups determine the chemical properties of the drug, and distinguishes individual types of bisphosphonates. This chemical structure affords a high affinity for calcium hydroxyapatite, allowing for rapid and specific skeletal targeting.

Bisphosphonates are a class of drugs that prevent the loss of bone density. They are the most commonly prescribed to treat osteoporosis and similar diseases.

Excerpted from Wikipedia’s “bisphosphonate” article, available under the CC BY-SA 4.0 licence.

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