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bromethalin

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Bromethalin is a neurotoxic rodenticide that damages the central nervous system.

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Encyclopedic overview

4 sections
Contents
  • History
  • Mechanism of action
  • Risk of poisoning to humans and pets
  • References

Bromethalin is a neurotoxic rodenticide that damages the central nervous system.

==History== Bromethalin was discovered in the early 1980s through an approach to find replacement rodenticides for first-generation anticoagulants, especially to be useful against rodents that had become resistant to warfarin-type anticoagulant poisons. A structured study was undertaken to develop a substance that would be both poisonous to rodents, but also would be readily eaten by rodents. Bromethalin—N-methyl-2,4-dinitro-N (2,4,6-tribromophenyl)-6-(trifluoromethyl) benzeneamine— was the outcome of that study, as the specific formulation had both desired rodenticidal properties.

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