Difethialone is an vitamin K antagonist anticoagulant used as a rodenticide. It is considered a second generation agent.
Difethialone is an vitamin K antagonist anticoagulant used as a rodenticide. It is considered a second generation agent.
It belongs to the 4-thiochromenone or benzothiopyranone class of rodenticides, which differs from 4-hydroxycoumarins by the substitution of an oxygen atom with sulfur. It is especially similar to brodifacoum. It shares the same mechanism of inhibiting Vkorc1. It is effective for warfarin-resistant and warfarin-susceptible rodents. Its high potency makes resistance harder to evolve, though a few populations of rodents have nevertheless managed to do so.
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).