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difethialone
Sign in to saveDifethialone is an vitamin K antagonist anticoagulant used as a rodenticide. It is considered a second generation agent.
Chemical data
- Formula
- C31H23BrO2S
- Molecular weight
- 539.5 g/mol
- IUPAC name
- 3-[3-[4-(4-bromophenyl)phenyl]-1,2,3,4-tetrahydronaphthalen-1-yl]-2-hydroxythiochromen-4-one
- SMILES
- C1C(CC2=CC=CC=C2C1C3=C(SC4=CC=CC=C4C3=O)O)C5=CC=C(C=C5)C6=CC=C(C=C6)Br
- InChIKey
- VSVAQRUUFVBBFS-UHFFFAOYSA-N
- XLogP
- 8.3
- Polar surface area
- 62.6 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 538.060213
Show 3 more facts
- chemical formula
- C₃₁H₂₃BrO₂S
- canonical SMILES
- Oc1c(C2CC(Cc3ccccc23)c2ccc(cc2)-c2ccc(Br)cc2)c(=O)sc2ccccc12
- Commons category
- Difethialone
via Wikidata · CC0
~3 min read
Encyclopedic overview
2 sectionsContents
- Regulations
- References
Difethialone is an vitamin K antagonist anticoagulant used as a rodenticide. It is considered a second generation agent.
It belongs to the 4-thiochromenone or benzothiopyranone class of rodenticides, which differs from 4-hydroxycoumarins by the substitution of an oxygen atom with sulfur. It is especially similar to brodifacoum. It shares the same mechanism of inhibiting Vkorc1. It is effective for warfarin-resistant and warfarin-susceptible rodents. Its high potency makes resistance harder to evolve, though a few populations of rodents have nevertheless managed to do so.
Excerpted from Wikipedia’s “difethialone” article, available under the CC BY-SA 4.0 licence.
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