cabotegravir
Sign in to saveAlso known as GSK744
Cabotegravir, sold under the brand name Vocabria among others, is an antiretroviral medication used for the treatment and prevention of HIV/AIDS. It is available in the form of tablets and as an intramuscular injection, as well as in an injectable combination with rilpivirine under the brand name Cabenuva.
Key facts
- Drug.image
- Cabotegravir (GSK744).svg
- Drug.image_class
- skin-invert-image
- Drug.image2
- Cabotegravir ball-and-stick model.png
- Drug.image_class2
- bg-transparent
- Drug.tradename
- Vocabria, Apretude
- Drug.MedlinePlus
- a621010
- Drug.DailyMedID
- Cabotegravir
- Drug.pregnancy_AU
- B1
- Drug.routes_of_administration
- By mouth, intramuscular
- Drug.ATC_prefix
- J05
- Drug.ATC_suffix
- AJ04
- Drug.legal_AU
- S4
- Drug.legal_CA
- Rx-only
- Drug.legal_US
- Rx-only
- Drug.legal_EU
- Rx-only
- Drug.protein_bound
- >99%
- Drug.metabolism
- UGT1A1
- Drug.metabolites
- glucuronide
via Wikipedia infobox
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 405.114
Show 5 more facts
- canonical SMILES
- CC1COC2N1C(=O)C3=C(C(=O)C(=CN3C2)C(=O)NCC4=C(C=C(C=C4)F)F)O
- chemical formula
- C₁₉H₁₇F₂N₃O₅
- isomeric SMILES
- C[C@H]1CO[C@H]2N1C(=O)C3=C(C(=O)C(=CN3C2)C(=O)NCC4=C(C=C(C=C4)F)F)O
- Commons category
- Cabotegravir
- legal status (medicine)
- boxed warning
via Wikidata · CC0
~8 min read
Encyclopedic overview
16 sectionsContents
- Medical uses
- Contraindications and interactions
- Adverse effects
- Pharmacology
- Mechanism of action
- Pharmacokinetics
- Pharmacogenomics
- Chemistry
- Formulation
- History
- Society and culture
- Legal status
- Names
- Research
- Pre-exposure prophylaxis
- References
Cabotegravir, sold under the brand name Vocabria among others, is an antiretroviral medication used for the treatment and prevention of HIV/AIDS. It is available in the form of tablets and as an intramuscular injection, as well as in an injectable combination with rilpivirine under the brand name Cabenuva.
It is an integrase inhibitor with a carbamoyl pyridone structure similar to that of dolutegravir.
Excerpted from Wikipedia’s “cabotegravir” article, available under the CC BY-SA 4.0 licence.