CALML5
Sign in to saveAlso known as CLSP, calmodulin like 5
Calmodulin-like protein 5 is a protein that in humans is encoded by the CALML5 gene.
In the Vinony graph
Vinony's link graph records 42 inbound references to CALML5, and connects out to PubMed, human chromosome 10 and keratinocyte.
It is catalogued under topics including EF-hand-containing proteins and Genes on human chromosome 10.
Vinony links it to 6 Wikipedia language editions.
Gene data
CALML5- Name
- calmodulin like 5
- Type
- protein-coding
- Position
- 5,498,697–5,499,570 (−)
- Aliases
- CLSP
- Ensembl
- ENSG00000178372
- RefSeq RNA
- NM_017422.5
- RefSeq protein
- NP_059118.2
This gene encodes a novel calcium binding protein expressed in the epidermis and related to the calmodulin family of calcium binding proteins. Functional studies with recombinant protein demonstrate it does bind calcium and undergoes a conformational change when it does so. Abundant expression is detected only in reconstructed epidermis and is restricted to differentiating keratinocytes. In addition, it can associate with transglutaminase 3, shown to be a key enzyme in the terminal differentiation of keratinocytes. [provided by RefSeq, Jul 2008].
Gene Ontology
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
calmodulin like 5
- Symbol
- CALML5
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 10:5,498,697-5,499,570
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein CALML5 PDB 2b1u.png
Show 8 more facts
- HomoloGene ID
- 49485
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/51806
- genomic end
- 5499570
- genomic start
- 5540658
- chromosome
- human chromosome 10
- cytogenetic location
- 10p15.1
- expressed in
- parotid gland
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- External links
- Further reading
Calmodulin-like protein 5 is a protein that in humans is encoded by the CALML5 gene.
This gene encodes a novel calcium binding protein expressed in the epidermis and related to the calmodulin family of calcium binding proteins. Functional studies with recombinant protein demonstrate it does bind calcium and undergoes a conformational change when it does so. Abundant expression is detected only in reconstructed epidermis and is restricted to differentiating keratinocytes. In addition, it can associate with transglutaminase 3, shown to be a key enzyme in the terminal differentiation of keratinocytes.
Excerpted from Wikipedia’s “CALML5” article, available under the CC BY-SA 4.0 licence.