CAPN5
Sign in to saveAlso known as ADNIV, HTRA3, VRNI, nCL-3, calpain 5
Calpain-5 is a protein that in humans is encoded by the CAPN5 gene.
Gene data
CAPN5- Name
- calpain 5
- Type
- protein-coding
- Position
- 77,066,961–77,126,155 (+)
- Aliases
- ADNIV, HTRA3, VRNI, nCL-3
- Ensembl
- ENSG00000149260
- RefSeq RNA
- NM_001425321.1, NM_001425322.1, NM_001425323.1, NM_004055.5, NR_189161.1
- RefSeq protein
- NP_001412250.1, NP_001412251.1, NP_001412252.1, NP_004046.2, XP_011543527.1
Calpains are calcium-dependent cysteine proteases involved in signal transduction in a variety of cellular processes. A functional calpain protein consists of an invariant small subunit and 1 of a family of large subunits. CAPN5 is one of the large subunits. Unlike some of the calpains, CAPN5 and CAPN6 lack a calmodulin-like domain IV. Because of the significant similarity to Caenorhabditis elegans sex determination gene tra-3, CAPN5 is also called as HTRA3. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
calpain 5
- Symbol
- CAPN5
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:77,066,961-77,126,155
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- Further reading
- External links
Calpain-5 is a protein that in humans is encoded by the CAPN5 gene.
Calpains are calcium-dependent cysteine proteases involved in signal transduction in a variety of cellular processes. A functional calpain protein consists of an invariant small subunit and 1 of a family of large subunits. CAPN5 is one of the large subunits. Unlike some of the calpains, CAPN5 and CAPN6 lack a calmodulin-like domain IV. Because of the significant similarity to Caenorhabditis elegans sex determination gene tra-3, CAPN5 is also called as HTRA3.
Excerpted from Wikipedia’s “CAPN5” article, available under the CC BY-SA 4.0 licence.