CBX1
Sign in to saveAlso known as CBX, HP1-BETA, HP1Hs-beta, HP1Hsbeta, M31, MOD1, p25beta, chromobox 1
Chromobox protein homolog 1 is a protein that in humans is encoded by the CBX1 gene.
Gene data
CBX1- Name
- chromobox 1
- Type
- protein-coding
- Position
- 48,070,052–48,107,848 (−)
- Aliases
- CBX, HP1-BETA, HP1Hs-beta, HP1Hsbeta, Hp1beta, M31, MOD1, p25beta
- Ensembl
- ENSG00000108468
- RefSeq RNA
- NM_001127228.2, NM_006807.5
- RefSeq protein
- NP_001120700.1, NP_006798.1
This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
chromobox 1
- Symbol
- CBX1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:48,070,052-48,107,848
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
6 sectionsContents
- Function
- Interactions
- See also
- References
- Further reading
- External links
Chromobox protein homolog 1 is a protein that in humans is encoded by the CBX1 gene.
== Function ==
Excerpted from Wikipedia’s “CBX1” article, available under the CC BY-SA 4.0 licence.