Gene data
CDC25C- Name
- cell division cycle 25C
- Type
- protein-coding
- Position
- 138,285,251–138,338,355 (−)
- Aliases
- CDC25, PPP1R60
- Ensembl
- ENSG00000158402
- RefSeq RNA
- NM_001287582.2, NM_001287583.2, NM_001318098.2, NM_001364026.1, NM_001364027.1
- RefSeq protein
- NP_001274511.1, NP_001274512.1, NP_001305027.1, NP_001350955.1, NP_001350956.1
This gene encodes a conserved protein that plays a key role in the regulation of cell division. The encoded protein directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It also suppresses p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described. [provided by RefSeq, Dec 2015].
Gene Ontology
Biological process
regulation of cyclin-dependent protein serine/threonine kinase activityG2/M transition of mitotic cell cycleG2/M transition of mitotic cell cycleG2/M transition of mitotic cell cycleG2/M transition of mitotic cell cycleregulation of mitotic nuclear divisioncell population proliferationcell population proliferation
Molecular function
Pathways
Cell cycle - Homo sapiens (human)Oocyte meiosis - Homo sapiens (human)Progesterone-mediated oocyte maturation - Homo sapiens (human)Human immunodeficiency virus 1 infection - Homo sapiens (human)MicroRNAs in cancer - Homo sapiens (human)Polo-like kinase mediated eventsSignal TransductionCell CycleDiseaseActivation of ATR in response to replication stress
via MyGene.info
Gene · Ensembl
cell division cycle 25C
- Symbol
- CDC25C
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 5:138,285,251-138,338,355
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein CDC25C PDB 3BZI.png
Show 7 more facts
- HomoloGene ID
- 1356
- exact match
- identifiers.org/ncbigene/995
- found in taxon
- Homo sapiens
- genomic end
- 137674044
- genomic start
- 137620954
- chromosome
- human chromosome 5
- cytogenetic location
- 5q31.2
Sources (4)
via Wikidata · CC0