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GeneQ18048823· pop 5· linked from 4 articles

Also known as H2A.Z-2, H2AV, H2A histone family member V, H2A.Z variant histone 2, H2AFV

Histone H2A.V is a protein that in humans is encoded by the H2AFV gene.

Gene data

H2AZ2
Name
H2A.Z variant histone 2
Type
protein-coding
Aliases
H2A.Z-2, H2AFV, H2AV

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. Several transcript variants encoding different isoforms, have been identified for this gene. [provided by RefSeq, Oct 2015].

via MyGene.info

Wikidata facts

Image
Protein H2AFV PDB 1f66.png
Show 5 more facts
HomoloGene ID
83271
genomic end
44887682
genomic start
44866390
cytogenetic location
7p13
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Histone H2A.V is a protein that in humans is encoded by the H2AFV gene.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H2A family. Several transcripts have been identified for this gene.

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