H2AZ2
Sign in to saveAlso known as H2A.Z-2, H2AV, H2A histone family member V, H2A.Z variant histone 2, H2AFV
Histone H2A.V is a protein that in humans is encoded by the H2AFV gene.
Gene data
H2AZ2- Name
- H2A.Z variant histone 2
- Type
- protein-coding
- Aliases
- H2A.Z-2, H2AFV, H2AV
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. Several transcript variants encoding different isoforms, have been identified for this gene. [provided by RefSeq, Oct 2015].
via MyGene.info
Wikidata facts
- Image
- Protein H2AFV PDB 1f66.png
Show 5 more facts
- HomoloGene ID
- 83271
- genomic end
- 44887682
- exact match
- identifiers.org/ncbigene/94239
- genomic start
- 44866390
- cytogenetic location
- 7p13
Sources (4)
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Histone H2A.V is a protein that in humans is encoded by the H2AFV gene.
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H2A family. Several transcripts have been identified for this gene.