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EntityQ912270· pop 29· linked from 258 articles

click chemistry

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Also known as link chemistry, speed-matching combinatorial chemistry

approach to chemical synthesis using highly favorable reactions involving components fitted with appropriate functional groups, which tolerates many functional groups that might complicate other coupling processes

Research

15,012 papers

via PubMed

~15 min read

Encyclopedic overview

Click chemistry is an approach to chemical synthesis that is used to join two molecules. The application of the term, click, as a qualifier to the type of chemistry refers to an emphasis on efficiency and simplicity. To link two molecular components, each is first fitted with appropriate functional groups, such as azide and alkyne groups. These components are then "clicked" together in a process that is highly favorable and which tolerates many functional groups that might complicate other coupling processes.

History

Excerpted from Wikipedia’s “click chemistry” article, available under the CC BY-SA 4.0 licence.