clomifene

Also known as Androxal®, Clomifenum, 2-(p-(β-chloro-α-phenylstyryl)phenoxy)triethylamine, Clomiphene, 2-(p-(2-chloro-1,2-diphenylvinyl)phenoxy)triethylamine, Clomifeno, 2-(4-(2-chloro-1,2-diphenylethenyl)phenoxy)-N,N-diethylethanamine

Clomifene, also known as clomiphene, is a medication used to treat infertility in women who do not ovulate, including those with polycystic ovary syndrome. It is taken by mouth.

Key facts

Drug.Verifiedfields: changed
Drug.Watchedfields: changed
Drug.verifiedrevid: 460044105
Drug.image: Clomiphene.svg
Drug.image_class: skin-invert-image
Drug.width: 250
Drug.class: Selective estrogen receptor modulator; Progonadotropin
Drug.ATC_prefix: G03
Drug.ATC_suffix: GB02
Drug.legal_AU: S4
Drug.legal_UK: POM
Drug.legal_US: Rx-only
Drug.bioavailability

~18 min read

Article

19 sections

Contents

Medical uses
Reproductive medicine
Testosterone replacement therapy
Gynecomastia
Prohibited use in sports
Contraindications
Side effects
Cancer risk
Pharmacology
Pharmacodynamics
Selective estrogen receptor modulator activity
Other activities
Pharmacokinetics
Chemistry
History
Society and culture
Brand names
Research
References

Clomifene, also known as clomiphene, is a medication used to treat infertility in women who do not ovulate, including those with polycystic ovary syndrome. It is taken by mouth.

Common side effects include pelvic pain and hot flashes. Other side effects can include changes in vision, vomiting, trouble sleeping, ovarian cancer, and seizures. It is not recommended in people with liver disease or abnormal vaginal bleeding of unknown cause or who are pregnant. Clomifene is in the selective estrogen receptor modulator (SERM) family of medication and is a nonsteroidal medication. It works by causing the release of GnRH by the hypothalamus, and subsequently gonadotropin from the anterior pituitary.