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کلاستبول

Structure via PubChem · Public domain (PubChem)

EntityQ422322· pop 15· linked from 598 articles

کلاستبول

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Also known as 4-chloro-17β-hydroxyandrost-4-en-3-one

Clostebol (; also known as 4-chlorotestosterone) is a synthetic anabolic–androgenic steroid (AAS). Clostebol is the 4-chloro derivative of the natural hormone testosterone. The chlorination prevents conversion to dihydrotestosterone (DHT) while also rendering the chemical incapable of conversion to estrogen. Although usually used as an ester including clostebol acetate (Macrobin, Steranabol, Alfa-Trofodermin, Megagrisevit), clostebol caproate (Macrobin-Depot), or clostebol propionate (Yonchlon), unmodified/non-esterified clostebol is also reported to be marketed, under the brand name Trofoderm

Chemical data

Formula
C19H27ClO2
Molecular weight
322.9 g/mol
IUPAC name
(8R,9S,10R,13S,14S,17S)-4-chloro-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
SMILES
C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=C(C(=O)CC[C@]34C)Cl
InChIKey
KCZCIYZKSLLNNH-FBPKJDBXSA-N
XLogP
4.2
Polar surface area
37.3 Ų
H-bond donors
1
H-bond acceptors
2
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Phase 2
Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Subclass of
steroid
Mass
322.17
Show 5 more facts
chemical formula
C₁₉H₂₇ClO₂
canonical SMILES
CC12CCC3C(C1CCC2O)CCC4=C(C(=O)CCC34C)Cl
Commons category
Clostebol
isomeric SMILES
C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=C(C(=O)CC[C@]34C)Cl
World Health Organisation international non-proprietary name
clostebol
Sources (3)

via Wikidata · CC0