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GeneQ18033962· pop 7· linked from 83 articles

COPB2

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Also known as beta'-COP, coatomer protein complex subunit beta 2, MCPH19, COPI coat complex subunit beta 2

Coatomer subunit beta is a protein that is encoded by the COPB2 gene in humans.

Gene data

COPB2
Name
coat protein complex I subunit beta 2
Type
protein-coding
Position
139,353,942–139,389,736 (−)
Aliases
MCPH19, OPDD, beta'-COP
Ensembl
ENSG00000184432
RefSeq RNA
NM_001410834.1, NM_004766.3, NR_023350.1, XM_047449233.1, XM_054348439.1
RefSeq protein
NP_001397763.1, NP_004757.1, XP_047305189.1, XP_054204414.1

The Golgi coatomer complex (see MIM 601924) constitutes the coat of nonclathrin-coated vesicles and is essential for Golgi budding and vesicular trafficking. It consists of 7 protein subunits, including COPB2.[supplied by OMIM, Jul 2002].

Gene Ontology

Pathways

ER to Golgi Anterograde TransportMembrane TraffickingMetabolism of proteinsAsparagine N-linked glycosylationVesicle-mediated transportPost-translational protein modificationCOPI-mediated anterograde transportCOPI-dependent Golgi-to-ER retrograde trafficIntra-Golgi and retrograde Golgi-to-ER trafficGolgi-to-ER retrograde transport

via MyGene.info

Gene · Ensembl

coat protein complex I subunit beta 2

Symbol
COPB2
Biotype
Protein coding
Organism
Homo sapiens
Location
3:139,353,942-139,389,736
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

~1 min read

Encyclopedic overview

5 sections
Contents
  • Function
  • Interactions
  • References
  • External links
  • Further reading

Coatomer subunit beta is a protein that is encoded by the COPB2 gene in humans.

== Function ==

Excerpted from Wikipedia’s “COPB2” article, available under the CC BY-SA 4.0 licence.

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