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GeneQ1181014· pop 5· linked from 356 articles

Also known as Dynamin-1, DNM, EIEE31, dynamin 1, DEE31

Dynamin-1 is a protein that in humans is encoded by the DNM1 gene.

Gene data

DNM1
Name
dynamin 1
Type
protein-coding
Position
128,191,655–128,255,254 (+)
Aliases
DEE31, DEE31A, DEE31B, DNM, EIEE31
RefSeq RNA
NM_001005336.3, NM_001288737.2, NM_001288738.2, NM_001288739.2, NM_001374269.1
RefSeq protein
NP_001005336.1, NP_001275666.1, NP_001275667.1, NP_001275668.1, NP_001361198.1

This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

dynamin 1

Symbol
DNM1
Biotype
Protein coding
Organism
Homo sapiens
Location
9:128,191,655-128,255,254
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Image
Protein DNM1 PDB 1dyn.png
Show 8 more facts
HomoloGene ID
123905
found in taxon
Homo sapiens
genomic end
131017527
genomic start
130965658
cytogenetic location
9q34.11
expressed in
postcentral gyrus
Sources (5)

via Wikidata · CC0

~1 min read

Encyclopedic overview

5 sections
Contents
  • Function
  • Role in disease
  • Interactions
  • References
  • Further reading

Dynamin-1 is a protein that in humans is encoded by the DNM1 gene.

== Function ==

Excerpted from Wikipedia’s “DNM1” article, available under the CC BY-SA 4.0 licence.

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