CUL7
Sign in to saveAlso known as 3M1, KIAA0076, dJ20C7.5, cullin 7, CUL-7
Cullin-7 is a RING-E3 ligase protein that in humans is encoded by the CUL7 gene.
Gene data
CUL7- Name
- cullin 7
- Type
- protein-coding
- Position
- 43,037,617–43,053,943 (−)
- Aliases
- 3M1, CUL-7, KIAA0076, dJ20C7.5
- Ensembl
- ENSG00000044090
- RefSeq RNA
- NM_001168370.2, NM_001374872.1, NM_001374873.1, NM_001374874.1, NM_014780.5
- RefSeq protein
- NP_001161842.2, NP_001361801.1, NP_001361802.1, NP_001361803.1, NP_055595.2
The protein encoded by this gene is a component of an E3 ubiquitin-protein ligase complex. The encoded protein interacts with TP53, CUL9, and FBXW8 proteins. Defects in this gene are a cause of 3M syndrome type 1 (3M1). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
cullin 7
- Symbol
- CUL7
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:43,037,617-43,053,943
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
5 sectionsContents
- Clinical significance
- Interactions
- References
- Further reading
- External links
Cullin-7 is a RING-E3 ligase protein that in humans is encoded by the CUL7 gene.
== Clinical significance == It is associated with 3-M syndrome.
Excerpted from Wikipedia’s “CUL7” article, available under the CC BY-SA 4.0 licence.