cyclazocine
Sign in to saveCyclazocine is a mixed opioid agonist/antagonist related to dezocine, pentazocine and phenazocine. It is in the benzomorphan and benzazocine family of drugs. It is a κ-opioid receptor agonist and μ-opioid receptor partial agonist, and also has high affinity for the δ-opioid receptor.
Research
1,118 papers- Cyclazocine revisited.Neurochemical research · 1996
- Cyclazocine and congeners.Advances in biochemical psychopharmacology · 1973
- Cyclazocine in the treatment of narcotic addiction.Current psychiatric therapies · 1967
- Cyclazocine and methadone in narcotic addiction.JAMA · 1967
- (+/-)Cyclazocine blocks the dopamine response to nicotine.Neuroreport · 1999
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Wikidata facts
- Mass
- 271.194
Show 3 more facts
- chemical formula
- C₁₈H₂₅NO
- canonical SMILES
- CC1C2CC3=C(C1(CCN2CC4CC4)C)C=C(C=C3)O
- Commons category
- Cyclazocine
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Article
2 sectionsContents
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Cyclazocine is a mixed opioid agonist/antagonist related to dezocine, pentazocine and phenazocine. It is in the benzomorphan and benzazocine family of drugs. It is a κ-opioid receptor agonist and μ-opioid receptor partial agonist, and also has high affinity for the δ-opioid receptor.
== Research == Research into the use of cyclazocine for the treatment of bipolar patients with depression was undertaken by Fink and colleagues (1970). It showed that 8 out of 10 patients experienced moderate improvement.