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nepinalone
Sign in to saveNepinalone is a cough suppressant. Its brand names include Placatus, Tussolvina, and Nepitus.
Chemical data
- Formula
- C18H25NO
- Molecular weight
- 271.4 g/mol
- IUPAC name
- 1-methyl-1-(2-piperidin-1-ylethyl)-3,4-dihydronaphthalen-2-one
- SMILES
- CC1(C(=O)CCC2=CC=CC=C21)CCN3CCCCC3
- InChIKey
- RVXGRCNWGOHSDE-UHFFFAOYSA-N
- XLogP
- 3.2
- Polar surface area
- 20.3 Ų
- H-bond donors
- 0
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- Cough
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 271.194
Show 2 more facts
- chemical formula
- C₁₈H₂₅NO
- canonical SMILES
- CC1(C(=O)CCC2=CC=CC=C21)CCN3CCCCC3
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Nepinalone is a cough suppressant. Its brand names include Placatus, Tussolvina, and Nepitus.
The effect is evident after 20–30 minutes after administration and persists for at least 4 hours. It acts primarily at the level of the CNS, but also shows a slight activity in inhibiting the bronchospasm. In such use, it is less effective than codeine and more effective than dextromethorphan in inhibiting the tussive stimulus.
Excerpted from Wikipedia’s “nepinalone” article, available under the CC BY-SA 4.0 licence.
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