CYP11B2

Also known as ALDOS, CPN2, CYP11B, CYP11BL, CYPXIB2, P-450C18, P450C18, P450aldo

protein-coding gene in the species Homo sapiens

In the Vinony graph

Within Vinony's link graph, CYP11B2 is referenced by 625 other articles, and connects out to cytochrome P450 family 11 subfamily B member 1, mitochondrion and steroid.

It is catalogued under topics including Cytochrome P450, Enzymes of known structure and Genes on human chromosome 8.

Its subject is documented across 7 Wikipedia language editions.

Gene data

CYP11B2

Name: cytochrome P450 family 11 subfamily B member 2
Type: protein-coding
Position: 142,910,424–142,917,943 (−)
Aliases: ALDOS, CPN2, CYP11B, CYP11BL, CYPXIB2, P-450C18, P450C18, P450aldo
Ensembl: ENSG00000179142
RefSeq RNA: NM_000498.3
RefSeq protein: NP_000489.3

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency. [provided by RefSeq, Jul 2008].